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MRI Volumetric Analysis of the Amygdala and Hippocampus Involving Verbal Memory in Parkinson's Patients
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by Christopher W. DeLisle, Mark A. Eckert, Tim H. Lucas, and Dawn Bowers* - Psychobiology Research Institute, University of Florida
Categories: Developmental | Physiological
This study attempted to determine if patients with Parkinson’s disease (PD) have smaller hippocampi and amygdalae than controls and if the size of these structures predicts verbal memory performance in patients. The amygdalae, hippocampi, and total brain volumes of 7 patients with PD were measured and compared with 7 controls. There were no significant differences in the volume of the amygdala and hippocampus for the 2 groups. The PD patients were also given the Hopkins Verbal Memory Test to determine the relation between verbal memory performance and volume of brain structures. Their scores were compared within the group for performance. A larger right hippocampus was related to impaired performance on the false-positive portion of the test. These results question the extent to which PD effects verbal memory performance in patients.