The purpose of this study was to determine the intercorrelations between religiosity, perceived family support, and self-esteem in adolescents. Using convenience sampling, we recruited the participants from three high schools and one church youth group in Southeast Louisiana. There were 93 participants (32 male and 61 female) ranging in age from 14 to 18 years. The participants filled out a demographic questionnaire, the Rosenberg Self-Esteem Scale, a Religiosity Scale, and the Perceived Social Support Family Scale. No significant correlation was found between religiosity and self-esteem. However, perceived family support and self-esteem had a significant positive correlation, as did perceived family support and religiosity. Male adolescents had lower religiosity than female adolescents. Suggestions for future research include investigating a more diverse sample and other possible variables.