This study examines the relationships among minor uplifts, daily hassles, and depressive symptoms in a sample of undergraduate college students as an extension of the Dixon and Reid (2000) study on major positive life events as a buffer to major negative life events in predicting depressive symptoms. Consistent with predictions, the results of a hierarchical multiple regression indicated a significant main effect for minor uplifts in predicting depressive symptoms such that increases in minor uplifts were associated with decreases in depressive symptoms. There was also a significant effect for daily hassles in predicting depressive symptoms such that increases in daily hassles were associated with increases in depressive symptoms. Contrary to predictions, there was not a significant interaction between daily hassles and minor uplifts in predicting depressive symptoms. However, daily hassles accounted for a significantly larger amount of variance in predicting depressive symptoms than did minor uplifts. This suggests minor negative events are more severe than minor positive events or those minor negative events are given much more weight than that of minor positive events.